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LY 345899
CAS No. 10538-99-5
LY 345899 ( —— )
Catalog No. M22500 CAS No. 10538-99-5
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 336 | In Stock |
|
| 10MG | 500 | In Stock |
|
| 25MG | 804 | In Stock |
|
| 50MG | 1098 | In Stock |
|
| 100MG | 1467 | In Stock |
|
| 500MG | 2952 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLY 345899
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NoteResearch use only, not for human use.
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Brief DescriptionLY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
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DescriptionLY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMTHFD1
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Research Area——
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Indication——
Chemical Information
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CAS Number10538-99-5
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Formula Weight471.42
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Molecular FormulaC20H21N7O7
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (265.16 mM; Need ultrasonic)
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SMILESNc1nc(=O)c2N3C(CN(C3=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schmidt A, et al. Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase. Biochemistry. 2000 May 30;39(21):6325-35.
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